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Inflammation-inducible promoters to overexpress immune inhibitory factors by MSCs

BACKGROUND: Mesenchymal stromal cells (MSCs) are excessively investigated in the context of inflammation-driven diseases, but the clinical results are often moderate. MSCs are naturally activated by inflammatory signals, which lead to the secretion of immune inhibitory factors in inflamed tissues. M...

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Detalles Bibliográficos
Autores principales: Selich, Anton, Fleischauer, Jenni, Roepke, Tina, Weisskoeppel, Luisa, Galla, Melanie, von Kaisenberg, Constantin, Maus, Ulrich A., Schambach, Axel, Rothe, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518110/
https://www.ncbi.nlm.nih.gov/pubmed/37742038
http://dx.doi.org/10.1186/s13287-023-03501-6