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LncRNA AC142119.1 facilitates the progression of neuroblastoma by epigenetically initiating the transcription of MYCN

BACKGROUND: Oncogene MYCN is closely related with malignant progression and poor prognosis of neuroblastoma (NB). Recently, long non-coding RNAs (lncRNAs) have been recognized as crucial regulators in various cancers. However, whether lncRNAs contribute to the overexpression of MYCN in NB is unclear...

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Detalles Bibliográficos
Autores principales: Yang, Rui, Liu, Nanjing, Li, Ting, Liu, Fangjie, Zhang, Jun, Zhao, Hui, Zou, Lin, He, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518117/
https://www.ncbi.nlm.nih.gov/pubmed/37741985
http://dx.doi.org/10.1186/s12967-023-04535-3