Orthosteric ligand selectivity and allosteric probe dependence at Hydroxycarboxylic acid receptor HCAR2

Hydroxycarboxylic acid receptor 2 (HCAR2), a member of Class A G-protein-coupled receptor (GPCR) family, plays a pivotal role in anti-lipolytic and anti-inflammatory effects, establishing it as a significant therapeutic target for treating dyslipidemia and inflammatory diseases. However, the mechani...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Lin, Sun, Suyue, Wang, Heli, Zhao, Chang, Tian, Xiaowen, Liu, Ying, Fu, Ping, Shao, Zhenhua, Chai, Renjie, Yan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518311/
https://www.ncbi.nlm.nih.gov/pubmed/37743365
http://dx.doi.org/10.1038/s41392-023-01625-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518311/
https://www.ncbi.nlm.nih.gov/pubmed/37743365
http://dx.doi.org/10.1038/s41392-023-01625-y

Ejemplares similares