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Orthosteric ligand selectivity and allosteric probe dependence at Hydroxycarboxylic acid receptor HCAR2

Hydroxycarboxylic acid receptor 2 (HCAR2), a member of Class A G-protein-coupled receptor (GPCR) family, plays a pivotal role in anti-lipolytic and anti-inflammatory effects, establishing it as a significant therapeutic target for treating dyslipidemia and inflammatory diseases. However, the mechani...

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Detalles Bibliográficos
Autores principales:	Cheng, Lin, Sun, Suyue, Wang, Heli, Zhao, Chang, Tian, Xiaowen, Liu, Ying, Fu, Ping, Shao, Zhenhua, Chai, Renjie, Yan, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518311/ https://www.ncbi.nlm.nih.gov/pubmed/37743365 http://dx.doi.org/10.1038/s41392-023-01625-y

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