Cargando…

Secreted LRPAP1 binds and triggers IFNAR1 degradation to facilitate virus evasion from cellular innate immunity

The crucial role of interferon (IFN) signaling is well known in the restriction or eradication of pathogen invasion. Viruses take a variety of ways to antagonize host defense through eliminating IFN-signaling intracellularly for decades. However, the way by viruses target IFN-signaling extracellular...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Huangcan, Wang, Xiong, Wang, Yiran, Li, Yichen, Chen, Ying, Wong, Yin-Ting, He, Jufang, He, Ming-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518340/
https://www.ncbi.nlm.nih.gov/pubmed/37743411
http://dx.doi.org/10.1038/s41392-023-01630-1