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Secreted LRPAP1 binds and triggers IFNAR1 degradation to facilitate virus evasion from cellular innate immunity
The crucial role of interferon (IFN) signaling is well known in the restriction or eradication of pathogen invasion. Viruses take a variety of ways to antagonize host defense through eliminating IFN-signaling intracellularly for decades. However, the way by viruses target IFN-signaling extracellular...
Autores principales: | Li, Huangcan, Wang, Xiong, Wang, Yiran, Li, Yichen, Chen, Ying, Wong, Yin-Ting, He, Jufang, He, Ming-Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518340/ https://www.ncbi.nlm.nih.gov/pubmed/37743411 http://dx.doi.org/10.1038/s41392-023-01630-1 |
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