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Intelligent tunable CAR-T cell therapy leads the new trend

Adoptive transfer of T cells engineered with chimeric antigen receptor (CAR) has been proved to have robust anti-tumor effects against hematological malignancies. However, problems about safety and efficacy, such as cytokine release syndrome (CRS), T cell exhaustion and antigen escape are still rais...

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Detalles Bibliográficos
Autores principales: Cheng, Jiayi, Liu, Mingyao, Zhang, Jiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518343/
https://www.ncbi.nlm.nih.gov/pubmed/37753197
http://dx.doi.org/10.1016/j.synbio.2023.09.001