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DNA damage repair profiling of esophageal squamous cell carcinoma uncovers clinically relevant molecular subtypes with distinct prognoses and therapeutic vulnerabilities

BACKGROUND: DNA damage repair (DDR) is a critical process that maintains genomic integrity and plays essential roles at both the cellular and organismic levels. Here, we aimed to characterize the DDR profiling of esophageal squamous cell carcinoma (ESCC), investigate the prognostic value of DDR-rela...

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Detalles Bibliográficos
Autores principales: Zhao, Ning, Zhang, Zicheng, Wang, Qiang, Li, Lin, Wei, Zichao, Chen, Hongyan, Zhou, Meng, Liu, Zhihua, Su, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518355/
https://www.ncbi.nlm.nih.gov/pubmed/37725855
http://dx.doi.org/10.1016/j.ebiom.2023.104801