Physicochemical Properties and Route of Systemic Delivery Control the In Vivo Dynamics and Breakdown of Radiolabeled Gold Nanostars

The in vivo dynamics of nanoparticles requires a mechanistic understanding of multiple factors. Here, for the first time, the surprising breakdown of functionalized gold nanostars (F-AuNSs) conjugated with antibodies and (64)Cu radiolabels in vivo and in artificial lysosomal fluid ex vivo, is shown....

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Detalles Bibliográficos
Autores principales: Wen, Xiaona, Ou, Luping, Cutshaw, Gabriel, Uthaman, Saji, Ou, Yu-Chuan, Zhu, Tian, Szakas, Sarah, Carney, Brandon, Houghton, Jacob, Gundlach-Graham, Alexander, Rafat, Marjan, Yang, Kai, Bardhan, Rizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518372/
https://www.ncbi.nlm.nih.gov/pubmed/36965074
http://dx.doi.org/10.1002/smll.202204293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518372/
https://www.ncbi.nlm.nih.gov/pubmed/36965074
http://dx.doi.org/10.1002/smll.202204293

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