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Innate mechanism of mucosal barrier erosion in the pathogenesis of acquired colitis

The colonic mucosal barrier protects against infection, inflammation, and tissue ulceration. Composed primarily of Mucin-2, proteolytic erosion of this barrier is an invariant feature of colitis; however, the molecular mechanisms are not well understood. We have applied a recurrent food poisoning mo...

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Detalles Bibliográficos
Autores principales: Yang, Won Ho, Aziz, Peter V., Heithoff, Douglas M., Kim, Yeolhoe, Ko, Jeong Yeon, Cho, Jin Won, Mahan, Michael J., Sperandio, Markus, Marth, Jamey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518488/
https://www.ncbi.nlm.nih.gov/pubmed/37752945
http://dx.doi.org/10.1016/j.isci.2023.107883