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A hydrogen–deuterium exchange mass spectrometry-based protocol for protein–small molecule interaction analysis

Protein–small molecule interaction is vital in regulating protein functions and controlling various cellular processes. Hydrogen deuterium exchange mass spectrometry (HDX-MS) is a powerful methodology to study protein–small molecule interactions, however, to accurately probe the conformational dynam...

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Detalles Bibliográficos
Autores principales: Meng, Qian, Song, Yuan-Li, Zhou, Chen, He, Han, Zhang, Naixia, Zhou, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biophysics Reports Editorial Office 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518522/
https://www.ncbi.nlm.nih.gov/pubmed/37753061
http://dx.doi.org/10.52601/bpr.2023.230006