Boosting NAD: An opportunity for metabolic reprogramming of Th17 cells in psoriatic disease

Metabolic reprogramming of CD4 T cells has become an opportunity for adjunctive therapies. Here, Han et al. show that boosting NAD(+) blunts systemic Th17 responses and increases antioxidant pathways through arginine and fumarate-mediated activation of NRF2 transcription factor.

Detalles Bibliográficos
Autor principal: Reali, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518578/
https://www.ncbi.nlm.nih.gov/pubmed/37729874
http://dx.doi.org/10.1016/j.xcrm.2023.101163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518578/
https://www.ncbi.nlm.nih.gov/pubmed/37729874
http://dx.doi.org/10.1016/j.xcrm.2023.101163

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