Osteoclast-derived apoptotic bodies inhibit naive CD8(+) T cell activation via Siglec15, promoting breast cancer secondary metastasis

The bone microenvironment promotes cancer cell proliferation and dissemination. During periodic bone remodeling, osteoclasts undergo apoptosis, producing large numbers of apoptotic bodies (ABs). However, the biological role of osteoclast-derived ABs, which are residents of the bone-tumor niche, rema...

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Detalles Bibliográficos
Autores principales: Wu, Yutong, Ai, Hongbo, Xi, Yuhang, Tan, Jiulin, Qu, Ying, Xu, Jianzhong, Luo, Fei, Dou, Ce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518580/
https://www.ncbi.nlm.nih.gov/pubmed/37607544
http://dx.doi.org/10.1016/j.xcrm.2023.101165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518580/
https://www.ncbi.nlm.nih.gov/pubmed/37607544
http://dx.doi.org/10.1016/j.xcrm.2023.101165

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