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A major role for CD4(+) T cells in driving cytokine release syndrome during CAR T cell therapy
Anti-CD19 chimeric antigen receptor (CAR) T cell therapy represents a breakthrough for the treatment of B cell malignancies. Yet, it can lead to severe adverse events, including cytokine release syndrome (CRS), which may require urgent clinical management. Whether interpatient variability in CAR T c...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518592/ https://www.ncbi.nlm.nih.gov/pubmed/37595589 http://dx.doi.org/10.1016/j.xcrm.2023.101161 |