Boosting NAD preferentially blunts Th17 inflammation via arginine biosynthesis and redox control in healthy and psoriasis subjects

To evaluate whether nicotinamide adenine dinucleotide-positive (NAD(+)) boosting modulates adaptive immunity, primary CD4(+) T cells from healthy control and psoriasis subjects were exposed to vehicle or nicotinamide riboside (NR) supplementation. NR blunts interferon γ (IFNγ) and interleukin (IL)-1...

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Detalles Bibliográficos
Autores principales: Han, Kim, Singh, Komudi, Meadows, Allison M., Sharma, Rahul, Hassanzadeh, Shahin, Wu, Jing, Goss-Holmes, Haley, Huffstutler, Rebecca D., Teague, Heather L., Mehta, Nehal N., Griffin, Julian L., Tian, Rong, Traba, Javier, Sack, Michael N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518596/
https://www.ncbi.nlm.nih.gov/pubmed/37586364
http://dx.doi.org/10.1016/j.xcrm.2023.101157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518596/
https://www.ncbi.nlm.nih.gov/pubmed/37586364
http://dx.doi.org/10.1016/j.xcrm.2023.101157

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