Metabolic classification suggests the GLUT1/ALDOB/G6PD axis as a therapeutic target in chemotherapy-resistant pancreatic cancer

Metabolic reprogramming is known as an emerging mechanism of chemotherapy resistance, but the metabolic signatures of pancreatic ductal adenocarcinomas (PDACs) remain unclear. Here, we characterize the metabolomic profile of PDAC organoids and classify them into glucomet-PDAC (high glucose metabolis...

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Detalles Bibliográficos
Autores principales: Li, Yunguang, Tang, Shijie, Shi, Xiaohan, Lv, Jingwen, Wu, Xueyuan, Zhang, Yehan, Wang, Huan, He, Juan, Zhu, Yiqin, Ju, Yi, Zhang, Yajuan, Guo, Shiwei, Yang, Weiwei, Yin, Huiyong, Chen, Luonan, Gao, Dong, Jin, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518604/
https://www.ncbi.nlm.nih.gov/pubmed/37597521
http://dx.doi.org/10.1016/j.xcrm.2023.101162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518604/
https://www.ncbi.nlm.nih.gov/pubmed/37597521
http://dx.doi.org/10.1016/j.xcrm.2023.101162

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