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The extracellular matrix in hepatocellular carcinoma: Mechanisms and therapeutic vulnerability
The tumor microenvironment (TME) is influenced by a “disorganized” extracellular matrix (ECM) that sensitizes cancer cells toward mechanical stress, signaling, and structural alterations. In hepatocellular carcinoma (HCC), lack of knowledge about key ECM proteins driving the TME refractory to target...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518608/ https://www.ncbi.nlm.nih.gov/pubmed/37652015 http://dx.doi.org/10.1016/j.xcrm.2023.101170 |