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The extracellular matrix in hepatocellular carcinoma: Mechanisms and therapeutic vulnerability

The tumor microenvironment (TME) is influenced by a “disorganized” extracellular matrix (ECM) that sensitizes cancer cells toward mechanical stress, signaling, and structural alterations. In hepatocellular carcinoma (HCC), lack of knowledge about key ECM proteins driving the TME refractory to target...

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Detalles Bibliográficos
Autores principales: Roy, Arya Mariam, Iyer, Renuka, Chakraborty, Sayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518608/
https://www.ncbi.nlm.nih.gov/pubmed/37652015
http://dx.doi.org/10.1016/j.xcrm.2023.101170