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Adenosine A2A receptor is a tumor suppressor of NASH-associated hepatocellular carcinoma

Inhibition of adenosine A2A receptor (A2AR) is a promising approach for cancer immunotherapy currently evaluated in several clinical trials. We here report that anti-obesogenic and anti-inflammatory functions of A2AR, however, significantly restrain hepatocellular carcinoma (HCC) development. Adora2...

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Detalles Bibliográficos
Autores principales: Allard, Bertrand, Jacoberger-Foissac, Célia, Cousineau, Isabelle, Bareche, Yacine, Buisseret, Laurence, Chrobak, Pavel, Allard, David, Pommey, Sandra, Ah-Pine, Franck, Duquenne, Sebastien, Picard, Fabien, Stagg, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518627/
https://www.ncbi.nlm.nih.gov/pubmed/37729873
http://dx.doi.org/10.1016/j.xcrm.2023.101188