Regulated adipose tissue-specific expression of human AGPAT2 in lipodystrophic Agpat2-null mice results in regeneration of adipose tissue

Genetic loss of Agpat2 in humans and mice results in congenital generalized lipodystrophy with near-total loss of adipose tissue and predisposition to develop insulin resistance, diabetes mellitus, hepatic steatosis, and hypertriglyceridemia. The mechanism by which Agpat2 deficiency results in loss...

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Detalles Bibliográficos
Autores principales: Agarwal, Anil K., Tunison, Katie, Vale, Goncalo, McDonald, Jeffrey G., Li, Xilong, Scherer, Philipp E., Horton, Jay D., Garg, Abhimanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518674/
https://www.ncbi.nlm.nih.gov/pubmed/37752957
http://dx.doi.org/10.1016/j.isci.2023.107806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518674/
https://www.ncbi.nlm.nih.gov/pubmed/37752957
http://dx.doi.org/10.1016/j.isci.2023.107806

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