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ALKBH5-mediated m(6)A demethylation of HS3ST3B1-IT1 prevents osteoarthritis progression

HS3ST3B1-IT1 was identified as a downregulated long noncoding RNA in osteoarthritic cartilage. However, its roles and mechanisms in the pathogenesis of osteoarthritis (OA) are unclear. In this study, we demonstrated that the expressions of HS3ST3B1-IT1 and its maternal gene HS3ST3B1 were downregulat...

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Detalles Bibliográficos
Autores principales: Tang, Yuting, Liu, Yang, Zhu, Xiaoshu, Chen, Yanlin, Jiang, Xinluan, Ding, Siyang, Zheng, Que, Zhang, Ming, Yang, Jiashu, Ma, Yunfei, Xing, Mengying, Zhang, Zongyu, Ding, Huimin, Jin, Yucui, Ma, Changyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518728/
https://www.ncbi.nlm.nih.gov/pubmed/37752950
http://dx.doi.org/10.1016/j.isci.2023.107838