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Fractionation of Native Protein Complexes from Mammalian Cells to Determine the Differential Proteasome Activity and Abundance

Eukaryotic cells have different types of proteasomes that differ in size. The smallest proteolytically active particle is the 20S proteasome, which degrades damaged and oxidized proteins; the most common larger particle is the 26S proteasome, which degrades ubiquitylated proteins. The 26S proteasome...

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Detalles Bibliográficos
Autores principales: Fiore, Ana Paula Zen Petisco, Vogel, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bio-Protocol 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518779/
https://www.ncbi.nlm.nih.gov/pubmed/37753477
http://dx.doi.org/10.21769/BioProtoc.4822