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α(1)-Antitrypsin deficiency associated with increased risk of heart failure

BACKGROUND: Individuals with α(1)-antitrypsin deficiency have increased elastase activity resulting in continuous degradation of elastin and early onset of COPD. Increased elastase activity may also affect elastic properties of the heart, which may impact risk of heart failure. We tested the hypothe...

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Detalles Bibliográficos
Autores principales: Winther, Sine V., Landt, Eskild M., Nordestgaard, Børge G., Seersholm, Niels, Dahl, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518873/
https://www.ncbi.nlm.nih.gov/pubmed/37753284
http://dx.doi.org/10.1183/23120541.00319-2023