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α(1)-Antitrypsin deficiency associated with increased risk of heart failure
BACKGROUND: Individuals with α(1)-antitrypsin deficiency have increased elastase activity resulting in continuous degradation of elastin and early onset of COPD. Increased elastase activity may also affect elastic properties of the heart, which may impact risk of heart failure. We tested the hypothe...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518873/ https://www.ncbi.nlm.nih.gov/pubmed/37753284 http://dx.doi.org/10.1183/23120541.00319-2023 |