miR155, TREM2, INPP5D: Disease stage and cell type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer’s amyloidopathy

Studies of microglial gene manipulation in mouse models of Alzheimer’s disease (AD) amyloidopathy can cause unpredictable effects on various key endpoints, including amyloidosis, inflammation, neuritic dystrophy, neurodegeneration, and learning behavior. In this Correspondence, we discuss three exam...

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Detalles Bibliográficos
Autores principales: Gandy, Sam, Ehrlich, Michelle E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518910/
https://www.ncbi.nlm.nih.gov/pubmed/37749581
http://dx.doi.org/10.1186/s12974-023-02895-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518910/
https://www.ncbi.nlm.nih.gov/pubmed/37749581
http://dx.doi.org/10.1186/s12974-023-02895-7

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