Cargando…
miR155, TREM2, INPP5D: Disease stage and cell type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer’s amyloidopathy
Studies of microglial gene manipulation in mouse models of Alzheimer’s disease (AD) amyloidopathy can cause unpredictable effects on various key endpoints, including amyloidosis, inflammation, neuritic dystrophy, neurodegeneration, and learning behavior. In this Correspondence, we discuss three exam...
Autores principales: | Gandy, Sam, Ehrlich, Michelle E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518910/ https://www.ncbi.nlm.nih.gov/pubmed/37749581 http://dx.doi.org/10.1186/s12974-023-02895-7 |
Ejemplares similares
-
Correction: miR155, TREM2, INPP5D: Disease stage and cell-type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer’s amyloidopathy
por: Gandy, Sam, et al.
Publicado: (2023) -
Alzheimer’s Amyloidopathy: An Alternative Aspect
por: Regland, Björn, et al.
Publicado: (2019) -
Oxidative stress: culprit or consequence in Alzheimer’s amyloidopathy
por: Sharma, Chanchal, et al.
Publicado: (2023) -
Microglial TYROBP/DAP12 in Alzheimer’s disease: Transduction of physiological and pathological signals across TREM2
por: Haure-Mirande, Jean-Vianney, et al.
Publicado: (2022) -
Microglial INPP5D limits plaque formation and glial
reactivity in the PSAPP mouse model of Alzheimer’s
disease
por: Castranio, Emilie L., et al.
Publicado: (2023)