Identification of candidate genes and chemicals associated with osteoarthritis by transcriptome-wide association study and chemical-gene interaction analysis

BACKGROUND: Osteoarthritis (OA) is a common degenerative joint disease and causes chronic pain and disability to the elderly. Several risk factors are involved, such as aging, obesity, genetic susceptibility, and environmental factors. We conducted a transcriptome-wide association study (TWAS) and c...

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Detalles Bibliográficos
Autores principales: Mei, Lin, Zhang, Zhiming, Chen, Ruiqi, Liu, Zhongyue, Ren, Xiaolei, Li, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518935/
https://www.ncbi.nlm.nih.gov/pubmed/37749624
http://dx.doi.org/10.1186/s13075-023-03164-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518935/
https://www.ncbi.nlm.nih.gov/pubmed/37749624
http://dx.doi.org/10.1186/s13075-023-03164-x

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