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SND1 aggravates mitochondrial damage, apoptosis and extracellular matrix degradation in IL-1β-stimulated chondrocytes via PINK1/BECN1 pathway

Recently, evidence has suggested a regulatory role for SND1 in osteoarthritis progression. Interestingly, we found that SND1 protein expression was increased, mitochondria were shrunken and decreased in number, mitochondrial membrane potential was decreased, mitochondrial ROS production was increase...

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Detalles Bibliográficos
Autores principales: Lin, Shufeng, Guo, Huiyang, You, Xiaoxuan, Zhang, Zefeng, Ye, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518936/
https://www.ncbi.nlm.nih.gov/pubmed/37749650
http://dx.doi.org/10.1186/s40001-023-01340-y