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High driving pressure ventilation induces pulmonary hypertension in a rabbit model of acute lung injury

BACKGROUND: Mechanical ventilation may cause pulmonary hypertension in patients with acute lung injury (ALI), but the underlying mechanism remains elucidated. METHODS: ALI was induced in rabbits by a two-hit injury, i.e., hydrochloric acid aspiration followed by mechanical ventilation for 1 h. Rabbi...

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Detalles Bibliográficos
Autores principales: Xu, Yonghao, Zhang, Yu, Zhang, Jie, Liang, Weibo, Wang, Ya, Zeng, Zitao, Liang, Zhenting, Ling, Zhaoyi, Chen, Yubiao, Deng, Xiumei, Huang, Yongbo, Liu, Xiaoqing, Zhang, Haibo, Li, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518953/
https://www.ncbi.nlm.nih.gov/pubmed/37749622
http://dx.doi.org/10.1186/s40560-023-00689-w