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Understanding the “individual drug reaction” from the perspective of the interaction between probiotics and lovastatin in vitro and in vivo

BACKGROUND: The existence of the gut microbiota produces an “individual drug reaction.” As members of the intestinal microbiota, probiotics, although they have prebiotic functions, may accelerate the degradation of drugs, thereby affecting drug efficacy. Lovastatin is one of the well-recognized lipi...

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Detalles Bibliográficos
Autores principales: Shen, Siyuan, Wang, Jun, Ma, Chenchen, Chen, Yanni, Ding, Hao, Zhang, Jiachao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518969/
https://www.ncbi.nlm.nih.gov/pubmed/37749663
http://dx.doi.org/10.1186/s40168-023-01658-z