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Drug metabolism-related gene ABCA1 augments temozolomide chemoresistance and immune infiltration abundance of M2 macrophages in glioma

Gliomas are the most prevalent primary tumor in the central nervous system, with an abysmal 5-year survival rate and alarming mortality. The current standard management of glioma is maximum resection of tumors followed by postoperative chemotherapy with temozolomide (TMZ) or radiotherapy. Low chemos...

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Detalles Bibliográficos
Autores principales: Yan, Yuanliang, Liu, Yuanhong, Liang, Qiuju, Xu, Zhijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518970/
https://www.ncbi.nlm.nih.gov/pubmed/37749600
http://dx.doi.org/10.1186/s40001-023-01370-6