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Convergent TP53 loss and evolvability in cancer
Cancer cell populations evolve by a stepwise process involving natural selection of the fittest variants within a tissue ecosystem context and as modified by therapy. Genomic scrutiny of patient samples reveals an extraordinary diversity of mutational profiles both between patients with similar canc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518978/ https://www.ncbi.nlm.nih.gov/pubmed/37743495 http://dx.doi.org/10.1186/s12862-023-02146-6 |