A fine-tuned yeast surface-display/secretion platform enables the rapid discovery of neutralizing antibodies against Clostridioides difficile toxins

BACKGROUND: Neutralizing antibody plays a key role in protecting hosts from invasive pathogens and their virulent components. Current high-throughput assays for antibody screening are based on binding activities. However, those antibodies with high affinity may not have neutralizing activities. Subs...

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Detalles Bibliográficos
Autores principales: Sun, Ying, Zhang, Yongrong, Yu, Hua, Saint Fleur, Ashley, Yu, Di, Yang, Zhiyong, Feng, Hanping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519002/
https://www.ncbi.nlm.nih.gov/pubmed/37749574
http://dx.doi.org/10.1186/s12934-023-02200-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519002/
https://www.ncbi.nlm.nih.gov/pubmed/37749574
http://dx.doi.org/10.1186/s12934-023-02200-4

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