MyD88 dimerization inhibitor ST2825 targets the aggressiveness of synovial fibroblasts in rheumatoid arthritis patients

BACKGROUND: Dimerization of the myeloid differentiation primary response 88 protein (MyD88) plays a pivotal role in the exacerbated response to innate immunity-dependent signaling in rheumatoid arthritis (RA). ST2825 is a highly specific inhibitor of MyD88 dimerization, previously shown to inhibit t...

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Detalles Bibliográficos
Autores principales: Ramirez-Perez, Sergio, Vekariya, Rushi, Gautam, Surabhi, Reyes-Perez, Itzel Viridiana, Drissi, Hicham, Bhattaram, Pallavi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519089/
https://www.ncbi.nlm.nih.gov/pubmed/37749630
http://dx.doi.org/10.1186/s13075-023-03145-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519089/
https://www.ncbi.nlm.nih.gov/pubmed/37749630
http://dx.doi.org/10.1186/s13075-023-03145-0

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