GMP-grade human neural progenitors delivered subretinally protect vision in rat model of retinal degeneration and survive in minipigs

BACKGROUND: Stem cell products are increasingly entering early stage clinical trials for treating retinal degeneration. The field is learning from experience about comparability of cells proposed for preclinical and clinical use. Without this, preclinical data supporting translation to a clinical st...

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Detalles Bibliográficos
Autores principales: Lu, Bin, Avalos, Pablo, Svendsen, Soshana, Zhang, Changqing, Nocito, Laura, Jones, Melissa K., Pieplow, Cosmo, Saylor, Joshua, Ghiam, Sean, Block, Amanda, Fernandez, Michael, Ljubimov, Alexander V., Small, Kent, Liao, David, Svendsen, Clive N., Wang, Shaomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519102/
https://www.ncbi.nlm.nih.gov/pubmed/37743503
http://dx.doi.org/10.1186/s12967-023-04501-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519102/
https://www.ncbi.nlm.nih.gov/pubmed/37743503
http://dx.doi.org/10.1186/s12967-023-04501-z

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