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Extravasation of Blood and Blood Toxicity Drives Tubular Injury from RBC Trapping in Ischemic AKI

Red blood cell (RBC) trapping is common in ischemic acute kidney injury (AKI) and presents as densely packed RBCs that accumulate within and engorge the kidney medullary circulation. In this study, we tested the hypothesis that “RBC trapping directly promotes tubular injury independent of extending...

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Detalles Bibliográficos
Autores principales: McLarnon, Sarah R, Johnson, Chloe, Sun, Jingping, Wei, Qingqing, Csanyi, Gabor, O'Herron, Phillip, Marshall, Brendan, Giddens, Priya, Sullivan, Jennifer C, Barrett, Amanda, O'Connor, Paul M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519276/
https://www.ncbi.nlm.nih.gov/pubmed/37753180
http://dx.doi.org/10.1093/function/zqad050