Integration site–dependent HIV-1 promoter activity shapes host chromatin conformation

HIV-1 integration introduces ectopic transcription factor binding sites into host chromatin. We postulate that the integrated provirus serves as an ectopic enhancer that recruits additional transcription factors to the integration locus, increases chromatin accessibility, changes 3D chromatin intera...

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Detalles Bibliográficos
Autores principales: Collora, Jack A., Ho, Ya-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519397/
https://www.ncbi.nlm.nih.gov/pubmed/37295842
http://dx.doi.org/10.1101/gr.277698.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519397/
https://www.ncbi.nlm.nih.gov/pubmed/37295842
http://dx.doi.org/10.1101/gr.277698.123

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