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Accurate sequencing of DNA motifs able to form alternative (non-B) structures

Approximately 13% of the human genome at certain motifs have the potential to form noncanonical (non-B) DNA structures (e.g., G-quadruplexes, cruciforms, and Z-DNA), which regulate many cellular processes but also affect the activity of polymerases and helicases. Because sequencing technologies use...

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Detalles Bibliográficos
Autores principales: Weissensteiner, Matthias H., Cremona, Marzia A., Guiblet, Wilfried M., Stoler, Nicholas, Harris, Robert S., Cechova, Monika, Eckert, Kristin A., Chiaromonte, Francesca, Huang, Yi-Fei, Makova, Kateryna D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519405/
https://www.ncbi.nlm.nih.gov/pubmed/37433640
http://dx.doi.org/10.1101/gr.277490.122