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Genome skimming with nanopore sequencing precisely determines global and transposon DNA methylation in vertebrates
Genome skimming is defined as low-pass sequencing below 0.05× coverage and is typically used for mitochondrial genome recovery and species identification. Long-read nanopore sequencers enable simultaneous reading of both DNA sequence and methylation and can multiplex samples for low-cost genome skim...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519409/ https://www.ncbi.nlm.nih.gov/pubmed/37442577 http://dx.doi.org/10.1101/gr.277743.123 |