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Recruitment of a Middling Promiscuous Enzyme Drives Adaptive Metabolic Evolution in Escherichia coli

A key step in metabolic pathway evolution is the recruitment of promiscuous enzymes to perform new functions. Despite the recognition that promiscuity is widespread in biology, factors dictating the preferential recruitment of one promiscuous enzyme over other candidates are unknown. Escherichia col...

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Detalles Bibliográficos
Autores principales: Campbell, Ryan P, Whittington, A Carl, Zorio, Diego A R, Miller, Brian G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519446/
https://www.ncbi.nlm.nih.gov/pubmed/37708398
http://dx.doi.org/10.1093/molbev/msad202