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Both MLH1 deficiency and BRAFV600E mutation are a unique characteristic of colorectal medullary carcinoma: An observational study

Although immunohistochemistry (IHC) for mismatch repair (MMR) proteins (MMR IHC) is used to identify DNA MMR status, universal screening of all patients with colorectal cancer (CRC) using a combination of both MMR IHC and genetic testing for the BRAFV600E mutation is limited in Japan. This study aim...

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Detalles Bibliográficos
Autores principales: Kaneko, Masanao, Nakashima, Mitsuko, Sugiura, Kiichi, Ishida, Natsuki, Tamura, Satoshi, Tani, Shinya, Yamade, Mihoko, Hamaya, Yasushi, Osawa, Satoshi, Tatsuta, Kyota, Kurachi, Kiyotaka, Baba, Satoshi, Iwashita, Yuji, Arai, Tomio, Sugimura, Haruhiko, Maekawa, Masato, Sugimoto, Ken, Iwaizumi, Moriya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519469/
https://www.ncbi.nlm.nih.gov/pubmed/37746995
http://dx.doi.org/10.1097/MD.0000000000035022