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2-iminobiotin, a selective inhibitor of nitric oxide synthase, improves memory and learning in a rat model after four vessel occlusion, mimicking cardiac arrest

Survivors of out-of-hospital cardiac arrest (OHCA) experience between 30% and 50% cognitive deficits several years post-discharge. Especially spatial memory is affected due to ischemia-induced neuronal damage in the hippocampus. Aim of this study was to investigate the potential neuroprotective effe...

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Detalles Bibliográficos
Autores principales: Peeters-Scholte, Cacha, Meilin, Sigal, Berckovich, Yafit, Westers, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519591/
https://www.ncbi.nlm.nih.gov/pubmed/37747911
http://dx.doi.org/10.1371/journal.pone.0291915