Adenovirus protein VII binds the A-box of HMGB1 to repress interferon responses

Viruses hijack host proteins to promote infection and dampen host defenses. Adenovirus encodes the multifunctional protein VII that serves both to compact viral genomes inside the virion and disrupt host chromatin. Protein VII binds the abundant nuclear protein high mobility group box 1 (HMGB1) and...

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Detalles Bibliográficos
Autores principales: Arnold, Edward A., Kaai, Robin J., Leung, Katie, Brinkley, Mia R., Kelnhofer-Millevolte, Laurel E., Guo, Monica S., Avgousti, Daphne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519595/
https://www.ncbi.nlm.nih.gov/pubmed/37703278
http://dx.doi.org/10.1371/journal.ppat.1011633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519595/
https://www.ncbi.nlm.nih.gov/pubmed/37703278
http://dx.doi.org/10.1371/journal.ppat.1011633

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