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Distinct disease features of acute and persistent genotype 3 hepatitis E virus infection in immunocompetent and immunosuppressed Mongolian gerbils

Hepatitis E virus (HEV) causes self-limited acute hepatitis in immunocompetent individuals and can establish chronic infection in solid organ transplant recipients taking immunosuppressive drugs. A well characterized small animal model is needed to understand HEV pathogenesis. In this study, we esta...

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Detalles Bibliográficos
Autores principales: Subramaniam, Sakthivel, Fares-Gusmao, Rafaelle, Sato, Shinya, Cullen, John M., Takeda, Kazuyo, Farci, Patrizia, McGivern, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519604/
https://www.ncbi.nlm.nih.gov/pubmed/37703304
http://dx.doi.org/10.1371/journal.ppat.1011664