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A pH-sensitive switch activates virulence in Salmonella

The transcriptional regulator SsrB acts as a switch between virulent and biofilm lifestyles of non-typhoidal Salmonella enterica serovar Typhimurium. During infection, phosphorylated SsrB activates genes on Salmonella Pathogenicity Island-2 (SPI-2) essential for survival and replication within the m...

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Detalles Bibliográficos
Autores principales: Shetty, Dasvit, Kenney, Linda J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519707/
https://www.ncbi.nlm.nih.gov/pubmed/37706506
http://dx.doi.org/10.7554/eLife.85690