(S)-Ketamine but Not (R)-Ketamine Shows Acute Effects on Depression-Like Behavior and Sleep-Wake Architecture in Rats

BACKGROUND: Racemic ketamine consists of two enantiomers, namely (R)-ketamine and (S)-ketamine, with distinguishable pharmacological properties. Both enantiomers have been reported to show rapid antidepressant effects in rodents. Currently, the (S)-enantiomer has been approved for the treatment of m...

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Detalles Bibliográficos
Autores principales: Koncz, Szabolcs, Papp, Noémi, Pothorszki, Dóra, Bagdy, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Regular Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519815/
https://www.ncbi.nlm.nih.gov/pubmed/37578355
http://dx.doi.org/10.1093/ijnp/pyad050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519815/
https://www.ncbi.nlm.nih.gov/pubmed/37578355
http://dx.doi.org/10.1093/ijnp/pyad050

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