Metabolic reprogramming contributes to radioprotection by protein kinase Cδ

Loss of protein kinase Cδ (PKCδ) activity renders cells resistant to DNA damaging agents, including irradiation; however, the mechanism(s) underlying resistance is poorly understood. Here, we have asked if metabolic reprogramming by PKCδ contributes to radioprotection. Analysis of global metabolomic...

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Detalles Bibliográficos
Autores principales: Ohm, Angela M., Affandi, Trisiani, Reisz, Julie A., Caino, M. Cecilia, D’Alessandro, Angelo, Reyland, Mary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519828/
https://www.ncbi.nlm.nih.gov/pubmed/37611829
http://dx.doi.org/10.1016/j.jbc.2023.105186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519828/
https://www.ncbi.nlm.nih.gov/pubmed/37611829
http://dx.doi.org/10.1016/j.jbc.2023.105186

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