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Protocol for the design, conduct, and evaluation of prime editing in human pluripotent stem cells
Prime editing introduces single-nucleotide polymorphism changes, small deletions, or insertions at a specific genome site without double-stranded DNA breaks or the need for the donor template. Here, we present a protocol to design, conduct, and evaluate prime editing in human pluripotent stem cells....
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519846/ https://www.ncbi.nlm.nih.gov/pubmed/37738119 http://dx.doi.org/10.1016/j.xpro.2023.102583 |