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Differences in hepatocellular iron metabolism underlie sexual dimorphism in hepatocyte ferroptosis

Males show higher incidence and severity than females in hepatic injury and many liver diseases, but the mechanisms are not well understood. Ferroptosis, an iron-mediated lipid peroxidation-dependent death, plays an important role in the pathogenesis of liver diseases. We determined whether hepatocy...

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Detalles Bibliográficos
Autores principales: Tao, Hui, Dar, Hamid Y., Tian, Cheng, Banerjee, Somesh, Glazer, Evan S., Srinivasan, Shanthi, Zhu, Liqin, Pacifici, Roberto, He, Peijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519854/
https://www.ncbi.nlm.nih.gov/pubmed/37741044
http://dx.doi.org/10.1016/j.redox.2023.102892