Cargando…
Comparative analysis of drug-salt-polymer interactions by experiment and molecular simulation improves biopharmaceutical performance
The propensity of poorly water-soluble drugs to aggregate at supersaturation impedes their bioavailability. Supersaturated amorphous drug-salt-polymer systems provide an emergent approach to this problem. However, the effects of polymers on drug-drug interactions in aqueous phase are largely unexplo...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519957/ https://www.ncbi.nlm.nih.gov/pubmed/37749228 http://dx.doi.org/10.1038/s42004-023-01006-0 |