Characterization and structure-based protein engineering of a regiospecific saponin acetyltransferase from Astragalus membranaceus

Acetylation contributes to the bioactivity of numerous medicinally important natural products. However, little is known about the acetylation on sugar moieties. Here we report a saponin acetyltransferase from Astragalus membranaceus. AmAT7-3 is discovered through a stepwise gene mining approach and...

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Detalles Bibliográficos
Autores principales: Wang, Linlin, Jiang, Zhihui, Zhang, Jiahe, Chen, Kuan, Zhang, Meng, Wang, Zilong, Wang, Binju, Ye, Min, Qiao, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519980/
https://www.ncbi.nlm.nih.gov/pubmed/37749089
http://dx.doi.org/10.1038/s41467-023-41599-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519980/
https://www.ncbi.nlm.nih.gov/pubmed/37749089
http://dx.doi.org/10.1038/s41467-023-41599-7

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