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Characterization and structure-based protein engineering of a regiospecific saponin acetyltransferase from Astragalus membranaceus
Acetylation contributes to the bioactivity of numerous medicinally important natural products. However, little is known about the acetylation on sugar moieties. Here we report a saponin acetyltransferase from Astragalus membranaceus. AmAT7-3 is discovered through a stepwise gene mining approach and...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519980/ https://www.ncbi.nlm.nih.gov/pubmed/37749089 http://dx.doi.org/10.1038/s41467-023-41599-7 |